The Best PCOS Supplements to Try in 2024

If you have the endocrine disorder PCOS (polycystic ovarian syndrome), you're aware of the disruptive, unpleasant symptoms it can cause, from issues getting pregnant to pesky acne and excessive hair growth.

While there is currently no cure for PCOS, there is strong evidence that PCOS supplements can help alleviate certain symptoms — the best way to supplement for the disorder is based on the type of PCOS you have and your symptoms (and that requires chatting with your physician).

How PCOS supplements may improve symptoms

PCOS is a condition in which ovaries have issues ovulating and where eggs are not released, says Dr. Aimee Eyvazzadeh, an OBGYN and medical advisor for fertility company Proov.

"The exact causes of PCOS are not fully understood. There is no cure for PCOS, but with prescribed medications, diet, supplements and lifestyle changes, PCOS can be managed well so women are symptom-free or nearly symptom-free."

Supplements that promote sugar metabolism and or ovarian function are ideal for PCOS patients. "They can help address the root causes of all the symptoms and lead to optimal symptom management and hormone balance," Eyvazzadeh says.

What to look for in the best PCOS supplements

Finding the ideal PCOS supplements to take is highly dependent on your symptoms. People with PCOS are believed to be deficient in some key vitamins and minerals, many of which affect factors like fertility and insulin resistance. Finding quality and safe supplements that are a good fit for your body may be helpful.

Opting for supplements that are National Sanitation Foundation (NSF) certified and United States Pharmacopeial Convention (USP) certified is key. Currently, the United States Food and Drug Administration (USFDA) does not test or approve supplements before they hit shelves.

So, what does that mean for you as a person trying to improve your overall health while battling PCOS symtoms? Buying supplements approved by the above-mentioned organizations ensures the products you’re purchasing pass the objective measures and strict criteria.

Dr. Eyvazzadeh recommends:

• Supplements that help with hormone balance, reducing estrogen and upping progesterone (and managing unwanted hair growth, testosterone levels and androgen levels)
• Supplements that promote optimal sugar metabolism and therefore ovarian function
• Supplements that contain alpha lipoic acid and Inositols to lower insulin and glucose levels

But as always, please consult your doctor before embarking on your PCOS supplement journey!

The best PCOS supplements to try now

• Best overall: Theralogix Ovasitol Inositol Powder Packets 
• Best budget: Zazzee Myo-Insitol Capsules 
• Best curcumin: Smarter Nutrition Curcumin Softgels
• Best blend: Bird&Be PCOS Support
• Best myo-inositol + D combo: Myo-Inositol & D-Chiro Inositol Blend Capsule
• Best coenzyme Q for PCOS: Doctor's Best High Absorption CoQ10 with BioPerine
• Best melatonin: Source Naturals Time Released Melatonin 2mg

Best overall

Theralogix Ovasitol Inositol Powder Packets

This powder supplement contains a unique blend of myo-inositol and D-chiro-inositol—a mix designed to support regular menstrual cycles, ovarian health and fertility. The Inositol fertility support supplement is ideal for women looking to promote healthy periods while aiding natural hormone levels and ovarian functions.

Made with premium ingredients, the USA-manufactured supplement is independently verified for potency and purity by the National Sanitation Foundation (NSF). It's also gluten-free, dye-free, vegan and contains no additives. We love that it's available in single-serve packets for ease.

Pros

• Powder supplement
• Unflavored
• Promote healthy periods, natural hormone levels and ovarian functions
• USA-manufactured
• NSF-certified
• Vegan formula

Cons

• Some reviewers say each packet doesn't include the same amount of powder

Best budget

Zazzee Myo-Insitol Capsules

This supplement is specifically formulated for women experiencing PCOS symptoms.  Made of 100% pure myo-Inositol, the capsules support healthy ovarian function, hormonal balance, a healthy menstrual cycle, egg quality and overall reproductive health.

The suggested daily dosage is 2000 mg of myo-Inositol (one capsule), which many clinical studies have shown to be the ideal dosage for fertility and reproductive support.

Designed to improve your overall well-being, the capsules help to support healthy mood balance, cognitive focus and increased energy. Best of all, the mid-sized capsule is super easy to swallow and is 100% vegetarian, made from cellulose that's derived from plants!

Pros

• Easy to swallow
• 120 capsules
• Daily dosage is ideal for fertility and reproductive support
• Unflavored
• USA-manufactured
• All natural, vegan, non-GMO formula

Cons

Best curcumin

Smarter Nutrition Curcumin Softgels

Curcumin is an active ingredient in turmeric that has anti-inflammatory, anti-oxidative stress, antibacterial and anti-apoptotic benefits. On its own, curcumin doesn't easily absorb in the body, which makes bioavailability a major issue. FYI: bioavailability is the amount of a substance that enters your bloodstream so you get the health benefits you're looking for.

To get the full benefits of curcumin, it must include the right support ingredients. Smarter Nutrition's softgels are a unique, holistic system specifically formulated with science-based ingredients—including black seed oil, ginger and sunflower lecithin—to help your body absorb curcumin’s benefits like a sponge.

Some doctors suggest pairing curcumin supplements with fatty fish oils (or just adding a serving or two of salmon to your plate each week).

Pros

• Uses active curcumin
• High bioavailability levels
• Provides digestive support
• All-natural ingredients
• Vegetarian formula (though can be combined with fish oil supplements other sources of omega-3 fatty acids)
• Also good for immune systems

Cons

• Doesn't last long (you need to take two capsules per day and there are 60 capsules in a bottle)

Best blend

Bird&Be PCOS Support

Bird&Be's PCOS Support supplement is formulated by fertility doctors to help regulate ovulation and menstrual cycles, while also supporting egg quality and insulin sensitivity — which means less of those pesky PCOS symptoms and better metabolic health.

The formula contains a therapeutic dose of four grams of myo-Inositol and 100 milligrams of D-chiro-Inositol at the 40:1 ratio recommended by fertility doctors., which has been proven as the most effective for managing PCOS symptoms.

Whether you’re trying to conceive or just managing the condition, PCOS Support has proven ingredients to help handle those hormones. Some women with PCOS who have tried this brand report reduced hair loss as well, which is a nice bonus.

Best of all, each box includes 30 convenient daily packets that are easy to integrate into your routine—just mix the taste-free powder into a cup of water and drink!

Pros

• Unflavored and taste-free powder
• Clinical doses of myo-Inositol and D-chiro-Inositol
• Promotes ovulation and supports egg quality
• Improves insulin sensitivity to help manage PCOS’ metabolic and hormonal symptoms
• Can be used when trying to conceive
• Made in Canada

Cons

• Only lasts one month, though we love this option so much we believe it's worth the slightly more expensive price

Best Myo-Inositol + D combo

Myo-Inositol & D-Chiro Inositol Blend Capsule

This best-selling supplement from Wholesome Story is a blend of 2,000 mg of myo-inositol and 50 mg of D-chiroi-inositol. Following the body's normal ratio of 40:1, it aims to support healthy hormone levels, ovarian health and menstrual cycles.

The 30-day supply of the premium inositol supplement is formulated with myo-inositol (for hormonal health) and D-Chiro Inositol (for menstrual and ovarian health.) Both inositols are naturally occurring compounds found in plant foods that can support healthy ovulation, contribute to becoming fertile and support overall reproductive health.

Reviewers have praised the product's abilities and how well it combines with other daily vitamins and supplements. Keep in mind, that it may take three to six months of using the supplement for you to see results!

Pros

• Supports hormonal health, menstrual cycle and ovarian health
• 100% natural ingredients
• Developed with the body's 40:1 ratio
• Vegan-friendly
• Blended in the US
• GMP (Good Manufacturing Practice) certified
• Many reviewers report reduced symptoms of PCOS

Cons

• Doesn't last long (you need to take four capsules per day and there are 120 capsules in a bottle)

Best coenzyme Q for PCOS

Doctor's Best High Absorption CoQ10 with BioPerine

CoQ10 is a fat-soluble natural vitamin — the easy-to-absorb nutrient powers and protects heart vitality, cardiovascular health and cellular energy. While its levels in the heart and body may begin to naturally decline after age 40, stress, free radicals and statin medication can impact CoQ10 levels — which, in turn, can have massive effects on those living with PCOS.

Formulated with BioPerine® black pepper extract, these capsules are designed to enhance absorption and bioavailability in the body. Better yet, CoQ10 has energizing antioxidant properties, which enhance vitality across many bodily systems, supporting brain health, immune performance, skin health, exercise capacity and gum health.

Pros

• Helps support heart health and cellular energy
• Helps restore depleted CoQ10 levels
• Enhance absorption and bioavailability
• Gluten-free formula
• Made in the USA, with globally-sourced ingredients
• Unflavored

Cons

• Some reviewers received capsules that were stuck together (implying they were exposed to heat)

Best melatonin

Source Naturals Time Released Melatonin

For those looking to catch some extra ZZZs among other benefits, a supplement infused with melatonin and myo-inositol — which you've read a lot about at this point — is the way to go. Source Naturals Melatonin is a non-habit-forming solution that helps reset the body's internal clock for those wanting relief from problems falling asleep and staying asleep.

In addition to calcium, melatonin works to sustain safe human gestation and provides a new way to prevent pregnancy-associated issues like gestational diabetes or anemia.

In addition, traditional cycles of melatonin production can be altered thanks to factors including aging, medications and light exposure at night. We love the clever time-released tablets that promise prolonged success. If this works for you, some docs suggest checking your levels of vitamin D as well.

 Pros

• Time-released tablets
• Affordable price
• Promotes healthy sleep
• Can last up to four months
• Unflavored
• Manufactured in the USA

Cons

• Time-released element varies on the individual